BP and Arterial Tone Improvement Is Observed In Adults Using CPAP Therapy

By on June 3, 2014

A new study has found out that there is rapid improvement in blood pressure and arterial tone in adult who are using continuous positive airway pressure (CPAP) therapy for treating Obstructive Sleep Apnea (OSA).

This research was performed under Dr. Ruth Benca’s and Dr. James Stein’s supervision and it was done at University of Wisconsin School of Medicine and Public Health.

CPAP Therapy - BP and Arterial ToneAnd Claudia Korcarz, DVM, RDCS, is the principal investigator of this research, who is also a manager and senior scientist at the University of Wisconsin Atherosclerosis Imaging Research Program (UW AIRP) in Madison.

According to the research, in sleep apnea patients who are having three months of CPAP therapy for Obstructive sleep apnea treatment, there was a significant reduction in systolic and diastolic blood pressures. And this treatment is also resulted in decrease of vascular tone and arterial stiffness.

After this, when the treatment was stopped for a week, these improvements were slowly reduced and reverted back to actual values prior to treatment.

Claudia Korcarz said that there was rapid improvement in blood pressure and arterial tone, which was observed as early as four weeks of CPAP therapy, and these improvements were reverted back in days after stopping the treatment.

Claudia Korcarz also said that these improvements were observed in young people with normal blood pressure levels. These finding demonstrates that the vascular effects that caused due to sleep apnea can be reversed with early treatment. There is possibility of easing the long term risks associated with chronic sleep apnea.

For this research, 47 adults with age around 41 years, who have been recently diagnosed with Obstructive Sleep Apnea, were studied. These adults were evaluated first before giving CPAP therapy for OSA treatment, 3 months after having treatment, and also after stopping the treatment for a week.

Value of Carotid to radial artery pulse wave velocity and central aortic blood pressures were obtained by applanation tonometry and Brachial artery size and flow-mediated dilation were measured with B-mode ultrasound.

These adults were told to use the CPAP therapy for at least 4hrs per night. 37 out them used the CPAP on an average of 6.1hrs per night. According to Korcarz, these findings showed that CPAP therapy, which is an effective treatment for sleep apnea can have positive implications for cardiovascular health.

Korcarz suggested that with early diagnosis and treatment of OSA with CPAP therapy in young adults with moderate to severe OSA, development of hypertension and other cardiovascular problems in future can be prevented.

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