4 Most Commonly Used Narcolepsy Treatment Drugs

By on April 7, 2015

Many people are aware of the fact that Narcolepsy is a very serious neurological disorder with symptoms that are prominent at a very young age. This is a condition where patients fall asleep instantly almost anywhere and at any place during the day.

Patients suffering from this condition are at an increased risk of developing infections, hormonal changes, trauma, immune system dysfunction and tumor growth. Medications are of good help in treating narcolepsy.

Common Narcolepsy Treatment Drugs

Some of the best known narcolepsy treatment drugs include:

Narcolepsy Treatment Drugs


Stimulants are the best Narcolepsy Treatment Drugs because they help in promoting alertness and wakefulness. Stimulants like Provigil or modafinil are effective in treating narcolepsy but they should not be taken by people suffering from psychosis, mania and depression.

Possible side effects of taking stimulants include nausea, headache, diarrhea and dry mouth.

Sodium Oxybate

Sodium Oxybate or Xylem is a very strong drug prescribed for severe narcolepsy. It is also called GHB and is considered quite safe in treating the condition.

Sodium oxybate promotes sound sleep, reduces incidences of cataplexy and diminishes daytime sleepiness. Nevertheless, it can have serious side effects like bed wetting, nausea and sleep walking.


Antidepressants used for treating depression might also be used as an effective treatment for narcolepsy. Antidepressants can work wonders in alleviating the symptoms of sleep paralysis, hallucinations and cataplexy.

Some powerful antidepressants used for treating narcolepsy include sertraline, venlafaxine and fluoxetine.

Tricylic Antidepressants

These are age-old antidepressants like clomipramine, protriptyline and imipramine that serve to be very effective in treating narcolepsy. However, these are drugs that can have serious side effects like lightheadedness and dry mouth.

This is the reason why they are not prescribed by doctors these days. It is best to go for the recent antidepressants available in the market because they do not have complicated side effects.